What are the long term side effects of phenytoin?

Long-term use of phenytoin also has been found to cause weakening of the bones. Bone disease is even more likely if a combination of seizure medicines is used.

Long-term side effects

  • overgrowth of the gums.
  • excessive hair on the face or body.
  • acne.
  • coarseness of facial features.

Does phenytoin cause memory loss?

All drugs that depress signaling in the CNS can cause memory loss. Alternatives: Many patients with seizures do well on phenytoin (Dilantin), which has little if any impact on memory.

What does phenytoin do to the brain?

Phenytoin works by slowing down impulses in the brain that cause seizures. Phenytoin is used to control seizures. It does not treat all types of seizures, and your doctor will determine if it is the right medicine for you.

Does phenytoin cause dementia?

Specifically, using therapies that are known to impair cognitive function correlated with a 20% greater risk of Alzheimer’s and a 60% greater risk of dementia. The most frequently used medications with known cognitive effects include primidone, phenytoin, carbamazepine, clonazepam, and valproate.

What are the adverse effects of phenytoin?

Headache, nausea, vomiting, constipation, dizziness, feeling of spinning, drowsiness, trouble sleeping, or nervousness may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Phenytoin may cause swelling and bleeding of the gums.

Is phenytoin a lifelong drug?

Phenytoin oral capsule is used for long-term treatment. It comes with serious risks if you don’t take it as prescribed. If you don’t take it at all or stop taking it: Stopping this drug suddenly or not taking it at all may cause serious problems, including having more seizures or seizures that don’t stop.

What are the 9 prescription drugs that cause dementia?

The study found that people had a higher risk for dementia if they took:

  • Antidepressants,
  • Antiparkinson drugs,
  • Antipsychotics,
  • Antimuscarinics (Used to treat an overactive bladder), and.
  • Antiepileptic drugs.

Who should not take phenytoin?

You should not use phenytoin if you are allergic to it, or if you have ever had: Tell your doctor if you have ever had: Some people have thoughts about suicide while taking phenytoin. Your doctor will need to check your progress at regular visits.

Is phenytoin a high risk medication?

The high-alert medications were: amiodarone, digoxin, dopamine, epinephrine, fentanyl, gentamycin, heparine, insulin, morphine, norepinephrine, phenytoin, potassium, propofol and tacrolimus.

What are the side effects of Dilantin 100 mg?

Headache, nausea, vomiting, constipation, dizziness, feeling of spinning, drowsiness, trouble sleeping, or nervousness may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Can phenytoin cause brain damage?

Conclusions: Cerebellar atrophy may be seen in phenytoin-exposed patients with epilepsy in the absence of generalized tonic-clonic seizures or preexistent brain damage.

Does Dilantin cause brain shrinkage?

Dilantin induced cerebellar atrophy is a devastating disease that impacts motor function, coordination, memory and the ability to speak. It is caused by Dilantin attacking neurons (nerve cells) in the cerebellum (the area of the brain that controls coordination and balance) causing them to deteriorate and die.

Can epilepsy affect your memory?

Any type of epileptic seizure could potentially affect your memory, either during or after a seizure. If you have lots of seizures, memory problems might happen more often. Some people have generalised seizures that affect all of the brain.

What is the major concern after administering phenytoin to a patient with seizure?

Nervous System: The most common adverse reactions encountered with phenytoin therapy are nervous system reactions and are usually dose-related. Reactions include nystagmus, ataxia, slurred speech, decreased coordination, somnolence, and mental confusion.

What is phenytoin 100mg used for?

Phenytoin is used to prevent and control seizures (also called an anticonvulsant or antiepileptic drug). It works by reducing the spread of seizure activity in the brain.

What causes phenytoin toxicity?

Phenytoin toxicity can occur from an increase in the daily dose of phenytoin, changes in the formulations or brands as well as changes in the frequency of administration. It can also occur when patients are started on new medications that interact with the metabolism or binding capacity of phenytoin to plasma proteins.

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